Your first drink of the night for a better tomorrow

Genetically engineered by a team of PhD microbiologists, ZBiotics® Pre-Alcohol is a probiotic drink that breaks down the byproduct of alcohol responsible for rough mornings after drinking.

Here’s to the hosts, the toasts, and a better tomorrow

Genetically engineered by a team of PhD microbiologists, ZBiotics® Pre-Alcohol is a probiotic drink that breaks down the byproduct of alcohol responsible for rough mornings after drinking.

Drink one tiny bottle before the big meal

Genetically engineered by a team of PhD microbiologists, ZBiotics® Pre-Alcohol is a probiotic drink that breaks down the byproduct of alcohol responsible for rough mornings after drinking.

Thankful for friends, family and GMOs

Genetically engineered by a team of PhD microbiologists, ZBiotics® Pre-Alcohol is a probiotic drink that breaks down the byproduct of alcohol responsible for rough mornings after drinking.

Our Products

Empower yourself from the inside out

Our growing lineup of engineered probiotics is designed to enrich busy lives everywhere.

Pre-Alcohol

Breaks down a toxic byproduct of alcohol called acetaldehyde while you drink and while you sleep — setting you up for a great next morning.

Sugar-to-Fiber

Produces an enzyme called levansucrase, which makes fiber using sugar from your diet, gently and all day long — improving microbiome health.

Our Mission

Better living through biotechnology

We’re giving people access to the power of biotechnology using GMO probiotics. And we’re changing the conversation in the process.

Learn More
ZBiotics

The Science

The world’s first genetically engineered probiotics: purpose-built to improve daily life.

  • Learn about Pre-Alcohol

    Learn More

    We start with a natural probiotic bacteria you already eat every day, called Bacillus subtilis. We then used a process naturally honed by bacteria to insert the instructions for making ALDH into the bacteria’s genome...

  • Learn about Sugar-to-Fiber

    Learn More

    Fiber plays an important role in our health but most of us aren’t getting enough fiber in our modern diets. We need 25-30 grams of fiber per day but about 95% of us don’t meet that goal...

Loved by thousands

“Sounds too good
to be true”

- Conrad D.

“You guys are going to love this”

- Mariah E.

“It quite literally has changed my life”

- Marcelo L.

“I always make sure I have a ZBiotics now”

- Matt S.

“We were all hugely impressed”

- Kristin A.

“I've gladly brought extra and shared with friends”

- Taylor W.

“After trying it once
I was hooked”

- Jordyn H.

“Made me wake up feeling really good”

- Brian B.

“We love ZBiotics”

- Ashley & Cody

You probably have some questions

Check out our FAQs to find answers to common questions and feel free to reach out if you have more.

Yes. We are excited to announce that we have launched our second product and now have two products, built with the same technology but for different purposes:

ZBiotics® Pre-Alcohol

For easier mornings after drinking.

Our original product, built to help you land on your feet the day after drinking alcohol by breaking down an unwanted byproduct called acetaldehyde while you drink and while you sleep—setting you up for a great next morning.

ZBiotics® Sugar-to-Fiber

For turning sugar into fiber in your gut

Our second product, newly launched to help you make the most of a modern diet by converting sugar you eat into fiber in your gut, gently and all day long—improving microbiome health.

ZBiotics Pre-Alcohol (or Pre-Alcohol for short) is a beverage containing a patented, genetically engineered probiotic (B. subtilis ZB183™) that helps you land on your feet the day after drinking alcohol. It’s engineered to break down an unwanted byproduct of alcohol called acetaldehyde – the main culprit behind rough mornings after drinking (citation).

Pre-Alcohol is designed to replicate the natural process of your liver, but do it in your gut. We took a normal probiotic bacteria you already eat every day, and we bioengineered it to produce the same type of enzyme your liver produces (citation). That enzyme breaks down acetaldehyde – an unwanted byproduct of alcohol that accumulates in your gut when you drink.

Your liver does not have access to your gut. But by drinking Pre-Alcohol, the goal is to augment your gut’s natural ability to digest acetaldehyde while you drink and while you sleep – helping you make the most of the next day. Just remember that Pre-Alcohol won’t affect intoxication or make alcohol safer to drink, so always drink responsibly.

Learn more about how Pre-Alcohol works.

ZBiotics Sugar-to-Fiber (or “Sugar-to-Fiber” for short) is a drink mix containing a patented, genetically engineered probiotic (B. subtilis ZB423™) that converts a small amount of the sugar you eat every day into fiber.

Specifically, Sugar-to-Fiber produces an enzyme called levansucrase, which breaks down molecules of a sugar called sucrose (also known as table sugar) and uses the components as building blocks to create a fiber called levan (a prebiotic fiber that is rare in most diets).

Sugar-to-Fiber contains a genetically engineered probiotic, Bacillus subtilis ZB423™, that takes a sugar called sucrose (table sugar) and uses it to create a fiber called levan. It does this by producing an enzyme called levansucrase.

When you mix Sugar-to-Fiber into your drink, the probiotic bacteria are naturally dormant and in a protective state called an endospore. The bacteria in this endospore form can travel safely through your stomach and make it to the intestines, where they will “wake up” and start producing the enzyme levansucrase. This enzyme is capable of breaking down the sucrose you consume into its two individual molecular components: glucose and fructose. It then strings together the free fructose molecules into long chains to make molecules of levan fiber.

Remember: at a molecular level, fibers are just long strings of simple sugars, but their different structures totally change how your body interacts with them. Levan is a rare and beneficial fiber that supports a healthy and diverse microbiome.

The primary benefits of Sugar-to-Fiber relate to microbiome health. Sugar-to-Fiber is unlikely to break down enough sugar to impact things like caloric intake, blood sugar, or weight. 

But it will impact your gut health. Sugar-to-Fiber provides exactly what we know makes your microbiome healthier: 

  1. More soluble fiber,
  2. More fiber diversity,
  3. Gradual delivery of fiber throughout the day, and
  4. Diversion of intestinal sugar

And the benefits of a healthier microbiome for your body are vast and vary from person to person: better immune function, improved gut-lining integrity, improved bowel function, increased short-chain fatty acid synthesis, better nutrient utilization, improved energy, psychological benefits such as greater desire to exercise and cravings for healthier foods, and more.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.