ZBiotics® Pre-Alcohol Probiotic Drink breaks down an unwanted alcohol byproduct called acetaldehyde – the primary culprit behind rough mornings after drinking.
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Gluten free
Nut free
Dairy free
Sugar free
Shellfish/Fish free
Vegan friendly
Third-party tested
Overall rating: 4.2254195 / 5 from 2085 reviews.
ZBiotics® Pre-Alcohol Probiotic Drink aims to reduce the negative effects of alcohol consumption, particularly acetaldehyde. Customer feedback varies on its effectiveness, with some reporting reduced hangover symptoms and others experiencing no significant difference or even adverse effects.
Review topics: [results, improvement, husband, taste, feeling, packaging, amount, service, customer service, bottle, stomach, issues, gift, relief, price, delivery, works, difference, effect, drink, zbiotics, hangover, alcohol, night, water, friends, morning, science, wine, shot].
"I’ve twice used this product and proceeded to drink a shameful amount of liquor. I had the time of my life both times (dancing + karaoke) and BOTH times I should have felt decrepit for weeks. Truly thankful to have found this product so I can continue to thrive on bad decisions when I make them every few months with my friends."
"I drank it before drinking alcohol. I do recommend it. It does help. I would like to have a little bit larger bottle of the pre-alcohol drink and a $4-$5 price point would be more reasonable to me. Let’s review ; a little more product for a more competitive price. Got it ? Great. ( well you did hit me up for a review several times and reviews are worthless without honesty). FYI I did recommend this pre-alcohol product to a few people I know. Thank you."
"I wish this product would help or work, but it just doesn’t seem to do anything for me or my wife. I love the idea and would gladly pay the high price for something that actually made a difference. Unfortunately, this just doesn’t do anything."
"We wanted to do a bulk order for our wedding and the company was amazing! Worked with us to do the order and provided labels specific to our wedding. Wonderful communication and fast turn around"
"I bought these before an event I go to in Vegas every year which tend to involve several happy hours followed by dinner followed by nightcaps. ZBiotics saved me the next day when I had to be on and professional. I heard about them on the Pod Save America Podcast and am so glad I tried ZBiotics!"
"I had a bottle a couple hours before drinking and the next day felt exactly as I would as if I had not taken it. I did not notice a difference in the aftermath of drinking (the next day); still felt the same after-effects as usual. I bought more than 1 bottle, so I'll keep giving it a chance. I am a bit disappointed in the current results. . Perhaps there should be a larger dosage."
"tried it both ways without Z biotics and with Z biotics and my mornings and evenings when I choose to drink are much better when I use antibiotics thank you so much for creating this product and I give it to all of my friends and we handed out at the spa as well"
"I was skeptical about using this at first because I did not know what to expect but I can tell you that this product works! I don't regularly drink but will on special occasions and just live with the "physiological consequences" the morning after. I woke up the morning after and went about my exercise training schedule and did not miss a beat nor felt fatigued! I was amazed and will use this again in the future!"
"I recently tried ZBiotics Pre-Alcohol to celebrate St. Patrick's Day in Chicago and at my Bachelorette Party in Scottsdale! Cannot say enough about how much better this made me feel the following day! As someone in my mid-30s who likes to imbibe for these occasions this is a game changer, and I highly recommend especially while traveling!"
"I had my doubts, but this stuff does what it says it does. You can enjoy a night out without ruining the next day. For the price of one drink, you can make your next day a good day. Amazing!"
Check out our FAQs to find answers to common questions and feel free to reach out if you have more.
Pre-Alcohol is a beverage containing a patented, genetically engineered probiotic (B. subtilis ZB183™) that helps you land on your feet the day after drinking alcohol. It’s engineered to break down an unwanted alcohol byproduct called acetaldehyde – the main culprit behind rough mornings after drinking.
Pre-Alcohol is designed to replicate the natural process of your liver, but do it in your gut. We took a normal probiotic bacteria you already eat every day, and we bioengineered it to produce the same type of enzyme your liver produces. That enzyme breaks down acetaldehyde – an unwanted byproduct of alcohol that accumulates in your gut when you drink.
Your liver does not have access to your gut. But by drinking Pre-Alcohol, the goal is to augment your gut’s natural ability to digest acetaldehyde while you drink and while you sleep – helping you make the most of the next day. Just remember that Pre-Alcohol does not affect intoxication or make alcohol safer to drink, so always drink responsibly.
When you're drinking. The earlier the better.
The probiotic in Pre-Alcohol needs time to “wake up” in your gut, so we say the earlier the better if you can remember it. We drink Pre-Alcohol just before going out – right before our first drink. But it should be active if you drink it any time during the day or evening. So whether it’s a few hours before drinking, right with your first drink, or even if you’ve already enjoyed a round or two, go for it.
The probiotic in Pre-Alcohol is likely to stay in your body for 18-24 hours after you drink it. So one bottle will cover you for a whole day, even if you're starting with brunch mimosas followed by evening plans later on!
Pre-Alcohol expires 18 months after bottling. Check the “BB” (Best-By) date on your bottle or box.
Store Pre-Alcohol at room temperature with the cap on. Do not refrigerate. Do not open it until you’re ready to drink it; opening it could potentially let contaminants from the air into the bottle.
Yes. Pre-Alcohol is fully FDA-compliant for safety and adheres to all regulatory requirements for sale in the U.S.
Note that FDA compliance is not FDA approval. FDA approval is a process reserved for drug products. Pre-Alcohol is a food/beverage product and has not been approved as efficacious for any purpose by the FDA.
FDA-compliant for safety means that we’ve satisfied all regulatory requirements to ensure Pre-Alcohol is safe and can be legally sold in the United States. That means that all our manufacturing is conducted in an FDA-registered food-grade facility according to Good Manufacturing Practices compliant with 21 CFR 117. It also means that our novel ingredient – Bacillus subtilis ZB183™ – has been extensively tested and is generally recognized, among qualified experts, as having been adequately shown to be safe under the conditions of its intended use.
No.
Pre-Alcohol will not affect your level of intoxication. Pre-Alcohol does not decrease your blood alcohol level, nor does it make alcohol any safer.
All the same rules about alcohol safety apply. Don’t get behind the wheel, don't operate heavy machinery, and don't drink too much. Alcohol is still dangerous on its own (citation).
That's not how it's designed.
We intentionally designed Pre-Alcohol so that it would not change your microbiome. We purposefully built our probiotic using a base bacteria that is well-adapted to passing straight through you and not colonizing your gut.
This creates a few likely benefits: (1) your microbiome remains unchanged; (2) the interaction between our probiotic and your gut should remain consistent and predictable; and (3) because we’re not trying to change your microbiome, we don’t need to use an excessive amount of probiotic per serving.
Yes!
We can confirm that Pre-Alcohol is free of all major allergens. Pre-Alcohol is tested, annually at minimum, against the allergens present in the manufacturing facility to ensure no cross-contamination. It does not contain:
Pre-Alcohol also doesn’t contain artificial flavors, and is vegan and vegetarian friendly.
Please note that our product contains live probiotic bacteria. As with any new food or supplement, it is always best to consult your medical doctor if you have any concerns related to your gut health with a new product.
Recommended pairing
Pre-Alcohol helps your nights. Sugar-to-Fiber helps your mornings by turning excess sugar into prebiotic fiber. Together they support all-day performance.
