Your first drink of the night for a better tomorrow

Genetically engineered by a team of PhD microbiologists, ZBiotics® Pre-Alcohol is a probiotic drink that breaks down the byproduct of alcohol responsible for rough mornings after drinking.

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Empower yourself from the inside out

Our growing lineup of engineered probiotics is designed to enrich busy lives everywhere.

Pre-Alcohol

Breaks down a toxic byproduct of alcohol called acetaldehyde while you drink and while you sleep — setting you up for a great next morning.

Our Mission

Better living through biotechnology

We’re giving people access to the power of biotechnology using GMO probiotics. And we’re changing the conversation in the process.

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ZBiotics

The Science

The world’s first genetically engineered probiotics: purpose-built to improve daily life.

  • Start with a Probiotic

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    We start with a natural probiotic bacteria you already eat every day, called Bacillus subtilis.

  • Edit its DNA

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    Next, we edit its DNA to make it do something unique and functional for your body.

  • Solve a Problem

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    Finally, each new probiotic we make goes into a new product, built to help you tackle a modern challenge of daily life.

Loved by thousands

“Sounds too good
to be true”

- Conrad D.

“You guys are going to love this”

- Mariah E.

“It quite literally has changed my life”

- Marcelo L.

“I always make sure I have a ZBiotics now”

- Matt S.

“We were all hugely impressed”

- Kristin A.

“I've gladly brought extra and shared with friends”

- Taylor W.

“After trying it once
I was hooked”

- Jordyn H.

“Made me wake up feeling really good”

- Brian B.

“We love ZBiotics”

- Ashley & Cody

You probably have some questions

Check out our FAQs to find answers to common questions and feel free to reach out if you have more.

ZBiotics Pre-Alcohol (or Pre-Alcohol for short) is a beverage containing a patented, genetically engineered probiotic (B. subtilis ZB183™) that helps you land on your feet the day after drinking alcohol. It’s engineered to break down an unwanted byproduct of alcohol called acetaldehyde – the main culprit behind rough mornings after drinking (citation).

Pre-Alcohol is designed to replicate the natural process of your liver, but do it in your gut. We took a normal probiotic bacteria you already eat every day, and we bioengineered it to produce the same type of enzyme your liver produces (citation). That enzyme breaks down acetaldehyde – an unwanted byproduct of alcohol that accumulates in your gut when you drink.

Your liver does not have access to your gut. But by drinking Pre-Alcohol, the goal is to augment your gut’s natural ability to digest acetaldehyde while you drink and while you sleep – helping you make the most of the next day. Just remember that Pre-Alcohol won’t affect intoxication or make alcohol safer to drink, so always drink responsibly.

Learn more about how Pre-Alcohol works.

The earlier the better. Ideally you drink Pre-Alcohol before your first drink.

The probiotic in Pre-Alcohol needs time to “wake up” in your gut, so we say the earlier the better if you can remember it. We drink Pre-Alcohol just before going out – right before our first drink. But it should be active if you drink it any time during the day or night. So whether it’s a few hours before drinking or you’ve already enjoyed a round or two, go for it. Pre-Alcohol can help from that point on.

The probiotic in Pre-Alcohol is likely to stay in your body for 18-24 hours after you drink it. So one bottle will cover you for a whole day, even if you're starting with brunch mimosas followed by evening plans later on!

Pre-Alcohol expires 18 months after bottling. Check the “BB” (Best-By) date on your bottle or box.

Store Pre-Alcohol at room temperature with the cap on. Do not refrigerate. Do not open it until you’re ready to drink it; opening it could potentially let contaminants from the air into the bottle.