Never miss a day again.

Subscribe to ZBiotics for dependable next-day insurance when you're drinking alcohol. Subscribers save 20% on every order.

Free shipping on US orders. 100% Money-Back Guarantee.

Never miss a day again.

Subscribe to ZBiotics for dependable next-day insurance when you're drinking alcohol. Subscribers save 20% on every order.

Free shipping on US orders. 100% Money-Back Guarantee.

Benefits of a Subscription

Never miss another morning

Get 6-pack or 12-packs of ZBiotics shipped to you automatically so you never run out of ZBiotics when you need it.

20% off every pack

The most economical way to get ZBiotics, at whatever frequency makes sense: from every 4 weeks to every 12 weeks.

Manage your subscription any time

Easily log into your account to make updates to your subscription, such as changing your quantity, updating your delivery date, or adjusting your frequency.

Notifications before each reorder

We text you before each reorder and help you easily skip if you're already fully stocked. So you're never caught getting extra product you don't want.

We text you before each reorder and help you easily skip if you're already fully stocked. So you're never caught getting extra product you don't want.

ZBiotics® Pre-Alcohol Probiotic Subscription

0.5 oz (15mL) per bottle

Subscribe and save 20% on ZBiotics® Pre-Alcohol Probiotic Drink. Not ready to subscribe? See one-time purchase options.

12-Pack

$7.17/bottle

BEST DEAL

6-Pack

$8/bottle

One-time Purchase

Subscribe & Save 20%

4 Weeks No commitment, cancel anytime
4 Weeks No commitment, cancel anytime
6 Weeks No commitment, cancel anytime
8 Weeks No commitment, cancel anytime
10 Weeks No commitment, cancel anytime

Free shipping on US orders - 100% Money-Back Guarantee

1. Have a ZBiotics

For best results, make ZBiotics your first drink of the night.

2. Drink Responsibly

Pace yourself, hydrate, and get a good night’s sleep.

3. Enjoy Tomorrow

Wake up feeling refreshed and ready to take on the day.

INGREDIENTS: Water, Natural Flavors, Potassium Sorbate, Sodium Chloride, Bacillus subtilis ZB183™ Probiotic

No sugar, calories, or random plant extracts. We built this from scratch so you know exactly what you’re getting: just engineered probiotic, water, and natural flavor.

Patented Technology: US 10,849,938 B2.

FDA-compliant for safety*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


With ZBiotics, I'm no longer playing Russian roulette with my productivity the next day. Life is too short to spend a whole day recovering.

Sophina T.

Scientist

ZBiotics has been such a huge help for me in reducing my anxiety around having a drink or two with friends during the week! What used to cause a very inevitable and very obvious drop in my productivity and creativity the next day is now an enjoyable, stress-free night with friends.

Kofi O.

Software engineer and singer/songwriter

One of the most practical and necessary synbio innovations yet - and yes, it actually works.

My husband and I don’t drink without it.

Abigail Y.

Startup Chief of Staff


How It Works

Real science, not just supplements.

Your liver is great at digesting acetaldehyde — the main culprit in those rough mornings after drinking. But unfortunately, most acetaldehyde accumulates in your gut, creating problems the next day.

So we used biotechnology to build a solution: a genetically engineered probiotic that produces the same type of enzyme as your liver. Simply put, it replicates your liver’s natural process where it matters most: your gut.

Have Questions?

ZBiotics is the first of its kind, and that’s bound to raise some questions. As scientists, curiosity is in our DNA, so we encourage you to ask your own and read our FAQ.

1. What is ZBiotics® Pre-Alcohol Probiotic?

ZBiotics® Pre-Alcohol Probiotic is a patented, genetically engineered probiotic that helps you land on your feet the day after drinking alcohol. It’s engineered to break down an unwanted byproduct of alcohol called acetaldehyde – the main culprit in those rough mornings after drinking.

2. How does ZBiotics work?

ZBiotics is designed to replicate the natural process of your liver, but do it in your gut. We took a normal probiotic bacteria you already eat every day, and we bioengineered it to produce the same type of enzyme your liver already produces. That enzyme breaks down acetaldehyde – an unwanted byproduct of alcohol that forms in your gut when you drink.

Your liver does not have access to your gut. But by putting ZBiotics directly in your gut, the goal is to augment your body’s natural ability to digest acetaldehyde while you drink and while you sleep – helping you make the most of the next day. Just remember that ZBiotics does not affect intoxication or make alcohol safer to drink, so always drink responsibly.

3. When do I drink ZBiotics?

When you're drinking. The earlier the better.

ZBiotics’ probiotics need time to “wake up” in your gut, so we say the earlier the better if you can remember it. We drink ZBiotics just before going out – right before our first drink. But ZBiotics should be active if you drink it any time during the day or evening, so a few hours before drinking, right with your first drink, or even if you’ve already enjoyed a round or two, go for it.